Apoaequorin Review

Is Apoaequorin Truly The Brain Vitamin We Hope It Is?

Description: Apoaequorin is a well known compound found in bioluminescent jellyfish. Studies have shown that it can help improve mental cognition, especially in the elderly.

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When scientists discovered apoaequorin, they won a Noble Peace Prize in 2008. To date, it is a controversial “brain vitamin” that numerous people have tried through a product called Prevagen by Quincy Bioscience. This “wonder supplement” helped the company become one of the fastest growing companies in the United States.


What Is Apoaequorin?

calcium binding proteinApoaequorin is a protein found in glowing jellyfish when it is bound to calcium ions. When the protein binds itself with the calcium ion, it produces the glow of the Aequorea victoria, a jellyfish with one of the simplest nervous system in the ecosystem. Quincy Bioscience claims though that their product, Prevagen, won’t make their customers glow like the bioluminescent jellyfish but instead, improve brain function.

Through experiment and research, scientists found that apoaequorin helped improve the cognitive function of the brain. This is especially effective, as they claimed, if taken by older people suffering from mild cognitive impairment. Younger people though are not prohibited from ingesting the compound as there have been reports of cognitive improvement among the younger group.

Apoaequorin is taken from a jellyfish, but researches claimed that the compound is “very similar in its amino acid sequence to a human endogenous calcium-binding protein.” What it simply states is that it is supposedly safe to be taken by human as the compound is already a familiar nutrient that the body takes from other sources.

What Are The Benefits Of Apoaequorin?

When ingesting it, there are known benefits that the human body can enjoy. One of which is the improved calcium homeostasis. Endogenous calcium is a very important component of the brain responsible for maintaining low levels of cytosolic calcium. When the level of cytosolic calcium increases, it would cause a diminished performance of the neuron cells.protect neurons from degradation

The decrease of endogenous calcium is a normal process associated with aging. Apoaequorin’s amino acid sequence, similar to endogenous calcium, helps by maintaining low levels of cytosolic calcium. It can help regulate intracellular calcium levels and protect neurons from degradation and its eventual death.

Studies have also shown that patients that took apoaequorin had an improved recall. The study claims that those suffering from mild to moderate mental impairment benefited most from the compound. The test results from those suffering from moderate to severe impairments failed to show a statistically significant improvement.

Through their research and studies, Quincy Bioscience claims that people who take their product Prevagen, the only known supplement with the jellyfish protein, can expect an improvement from absent mindedness, memory, and mild memory problems. They also claim that there are still unknown benefits from taking it.go-to-prevagen-review-article

Is It Safe To Take?Is It Safe?

Prevagen is the only supplement to incorporate apoaequorin as its main active ingredient. It is one of the most talked about memory boosting supplement in the market. It is also a very controversial one. It promises improvement in memory and attention, something that a lot of people crave for, whether it’s for their daily schedule, or for old people trying to enjoy their golden years.

Quincy Bioscience claims that there are no known interactions between Prevagen and other prescription medications. They caution, though, that before trying their supplement with prescription medications, it is imperative to consult their physicians first. Unknown results might occur that could be detrimental to the person taking it.

The company also claims that the supplement is safe and well tolerated by the body since it is safe enough to be ingested and classified as a food ingredient. There have been reports though of major side effects for those who took the supplement.

It is also stated that apoaequorin is non-allergenic. Those with known allergic reactions with fishshould not worry since the component is found on a jellyfish. A jellyfish is not a fish, but a Cnidaria, a completely different phylum from fishes.

Is It Vegetarian, Does It Contain Jellyfish?

For anyone worrying about harming jellyfish or if it is suitable for vegetarians the answer is a happy one!  The protein is grown under scientific conditions without the need for actual jellyfish and the product Prevagen is a vegetarian product, produced in a non gelatin capsule with a gluten free rice flour used as a filler.

Any Recent Controversies?Any downsides? Cons?

In recent years, Quincy Bioscience has been under fire from the United States Food and Drug Administration (FDA). When this news was revealed to the public, people taking the supplement were advised to consult their physicians about the supplement with regard to their current health and mental disposition.

Though Quincy Bioscience claims that there are no known side effects from using Prevagen, there have been reports of people suffering “seizures, strokes, and worsening symptoms of multiple sclerosis”, all of which are severe conditions that could be fatal if not treated early and properly. Other side effects include chest pains, tremors, fainting, and other serious symptoms.

The controversy arose when the FDA claimed that Quincy Bioscience failed to disclose the reported side effects of taking Prevagen. The FDA claims that reports and complaints have been made with the company by concerned users but “only investigated or reported two events.” Between May 2008 and December 2011, there have been more than 1000 incidents of these side effects.

Prevagen contains apoaequorin, a known compound from a bioluminescent jellyfish. However, the compound found in the supplement is only a synthetic form of apoaequorin. The FDA claims that since this content is only synthetic, it should be classified as a drug and not a supplement, thus should be under the strict approval requirement of the FDA.

Should You Take Apoaequorin?

Companies are known to exaggerate the efficacy of their products. This is a way to boost their sales and get a strong following in the market. However, this practice must be used with caution as certain complications may arise when their promises are not met. Even worse, when their products produce adverse effects that their customers definitely did not expect, they would be under intense heat.apoaequorin

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This is the case with Quincy Bioscience. There have been mixed reviews regarding the efficacy of Prevagen. Some reviews claim that it worked wonders for them. While the others claim that it failed to deliver its promise. The 30-90 day waiting time is just too long for some to claim as effective, and the price of the supplement is just too much. 

Up to now, Quincy Bioscience still maintains its position that their product is safe and has no known side effects. However, there have been reports of major side effects that prompted the FDA to warn Quincy Bioscience to state these reports to the public.

The compound suffers a blow in its reputation because of this controversy. Further research and tests are still necessary to determine whether this protein is actually safe and can deliver absolute mental improvement without the risk of any side effects.

The final choice is yours to make.  Try it and see if it works for you by following the product link below or find a different brain supplement from the vast amount available out there.  If you need help finding an alternative follow this link and read through some of our other reviews to find a suitable one for you.  Our top pick is a 100% natural supplement by Native Remedies called Focus Formula.







  1. Don O'Malley March 21, 2015
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